XKH001

Epithelium-derived cytokine IL-25 (also known as IL-17E) is one of central regulators for Type 2 immunity, providing important tissue-specific signals to both innate and adaptive cell populations throughout type 2 inflammation.

XKH001 is designed to bind to human IL-25 and block its interaction with IL-17RB/RA to prevent subsequent signaling activity, thereby inhibiting IL-25-induced type 2 inflammation

XKH001 is the only IL-25 targeted drug in the world that has entered clinical development stage, and it has obtained IND approval in both China and the United States. XKH001 is expected to provide a more precise and better treatment option for patients type 2 inflammatory diseases worldwide.

XKH001 patent applications have been submitted in several major countries, with patent granted in three countries, and the rest are in the substantive examination stage


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